Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point
نویسندگان
چکیده
منابع مشابه
Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point
Vascular remodeling under conditions of growth or exercise, or during recovery from arterial restriction or blockage is essential for health, but mechanisms are poorly understood. It has been proposed that endothelial cells have a preferred level of fluid shear stress, or 'set point', that determines remodeling. We show that human umbilical vein endothelial cells respond optimally within a rang...
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ژورنال
عنوان ژورنال: eLife
سال: 2015
ISSN: 2050-084X
DOI: 10.7554/elife.04645